Differential expression of FCRLA in naïve and activated mouse B cells
نویسندگان
چکیده
منابع مشابه
Activated mouse B cells lack expression of granzyme B.
Recently, it has been reported that human B cells express and secrete the cytotoxic protease granzyme B (GrB) after stimulation with IL-21 and BCR cross-linking. To date, there are few clues on the function of GrB in B cell biology. As experimental transgenic murine systems should provide insights into these issues, we assayed for GrB in C57BL/6 B cells using an extensive array of physiological...
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Differential expression of proteinase inhibitor-9 and granzyme B mRNAs in activated immunocompetent cells.
The role of proteinase inhibitor (PI)-9 in hematopoietic cells remains unclear. To clarify the role of PI-9 in these cells, we compared the expressions of PI-9 mRNA and antigen with those of granzyme B (GrB). While the strongest expression of PI-9 mRNA was observed in a NK cell line YT-N10, it was also expressed in a B-acute lymphoblastic leukemia cell line U-Tree02, an Epstein-Barr Virus (EBV)...
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ژورنال
عنوان ژورنال: Cellular Immunology
سال: 2012
ISSN: 0008-8749
DOI: 10.1016/j.cellimm.2011.10.013